Proposition 65

Proposition 65, officially known as the Safe Drinking Water and Toxic Enforcement Act of 1986, was enacted as a ballot initiative in November 1986. The proposition protects the state's drinking water sources from being contaminated with chemicals known to cause cancer, birth defects or other reproductive harm, and requires businesses to inform Californians about exposures to such chemicals.

Proposition 65 requires the state to maintain and update a list of chemicals known to the state to cause cancer or reproductive toxicity.


Questions about Proposition 65? Check our Frequently asked Questions page or visit our Proposition 65 Warnings website

About Proposition 65

The Safe Drinking Water and Toxic Enforcement Act

The Proposition 65 List

The current Proposition 65 list is dated March 19, 2021

Meetings, Hearings and Workshops

Upcoming and past meetings, hearings and workshops


All Proposition 65 Notices

Laws and Regulations

Links and downloads related to Proposition 65 statute and regulations


Visit this website to learn about warnings for exposures to chemicals on the Proposition 65 List

How chemicals are added to the Proposition 65 list

Learn how chemicals are added to the list

Authoritative Bodies Tracking Table

Contains information on the status of chemicals considered by OEHHA for addition to the Proposition 65 list

Safe Use Determinations

A Safe Use Determination (SUD) is a written statement issued by OEHHA, which interprets and applies Proposition 65 and its implementing regulations to a specific set of facts in response to a request by a business or a trade group

Interpretive Guidelines for Proposition 65

An Interpretive Guideline interprets Proposition 65 and its implementing regulations, as applied to specific facts

New Warning Regulations

Clear and reasonable warnings

Searchable Proposition 65 Chemical Database

Search the Proposition 65 Chemical Database

Safe harbor levels

Current Proposition 65 No Significant Risk Levels (NSRLs) Maximum Allowable Dose Levels (MADLs)


Upcoming Events

Reports, Notices, Documents

Jun 11, 2021: Notice of Intent to List Chemicals by the Labor Code Mechanism: Tetrahydrofuran; 2-ethylhexyl Acrylate; Methyl Acrylate; and Trimethylolpropane Triacrylate, Technical Grade
The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) intends to list the following chemicals as known to the state to cause cancer under the Safe Drinking Water and Toxic Enforcement Act of 1986: Tetrahydrofuran, 2-Ethylhexyl acrylate, Methyl acrylate, Trimethylolpropane triacrylate.