California Medical Supervision Program

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Pesticides handling and spraying

The California Medical Supervision program is designed to protect workers who regularly mix, load, or apply the highly toxic Category I and Category II organophosphate (OP) and N-methyl carbamate pesticides (CB).  The goal of the program is to identify and prevent excessive OP and CB exposure and resulting pesticide-related illness.  Exposure to OPs or CBs may lower the level of available cholinesterase (ChE) -- an enzyme essential to the proper functioning of the nervous system. Depression of cholinesterase levels can lead to symptoms ranging from blurred vision, diarrhea and tremors to seizures, loss of consciousness and even death. Monitoring plasma and red blood cell ChE levels allows detection of cholinesterase depression prior to the onset of illness.

Learn more about the program.



NEW! Effective January 1, 2017, physicians that have contract(s) with one or more employers to provide medical supervision services are required to register with OEHHA.

The list of registered medical supervisors can be found here.

All new requirements and responsibilities can be found here.


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